Jellagen - Products and Applications
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Jellagen is a Leading Provider of Jellyfish Collagen
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Next Generation Collagen for Next Generation Science
 
Jellagen produces research grade functional non-mammalian collagen products sourced from jellyfish. Jellagen's jellyfish collagen products are supplied to the cell culture and regenerative medicine research markets.
 
Jellagen jellyfish collagen has similar proliferation characteristics, induces the same morphology in cells and is not cytotoxic and is viable alternative to mammalian collagen.
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Pricing and Availability: Please contact us for pricing and availability on any of the Jellagen's range of products.
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For detailed information go to the Jellagen website:
Go to Oxford Genetics website
www.jellagen.co.uk
Why Jellyfish Collagen?
Core Technology: Fibrillar collagens such as type I, II, III and V exist as a triple helix. These form strong fibers that can be made into structures with low antigenicity, excellent biocompatability and biodegradability, making collagen a highly versatile biomaterial. The extraction process for Jellagen’s non-mammalian collagen preserves its triple helix structure ensuring a functional collagen.
 
Jellagen is able to produce jellyfish collagen on a large scale due to innovative manufacturing procedures, which have been developed by working with industry and academic partners. Their process currently produces >90% pure high quality native collagen, suitable for cell culture and research use.
 
Advantages of Jellyfish Collagen over Rat Tail Collagen: Whilst rat tail collagen may provide an effective extracellular matrix (ECM) for cell attachment, migration and proliferation for effective in-vitro cell culture studies, however, a signifcant limitation of rat tail collagen is not human biocompatible and cannot be replicated as effectively in a human in-vivo model.
 
Advantages of Jellyfish Collagen over Mammalian Collagen: Researchers who require to transfer their in-vitro model in to a human patient and develop an in-vivo model will need to be aware of the risks that mammalian collagen poses. Bovine for example, carries the risk of BSE and otehr transmissable viruses. Jellagen believe that jellyfish serve as an ideal source of collagen as the biomaterial is non-mammalian and disease free. Jellyfish are also considered a pest species to the marine environment and production of commercial volumes does not require high volume fishing of jellyfish species keeping the marine environment intact. Jellagen have conducted two studies:
 
Study 1. To compare the proliferation and morphological characteristics of cells grown on jellyfish collagen versus rat tail collagens.
Study 2. To compare cytotoxicity of jellyfish collagen versus bovine to demonstrate biocompatibility.
 
These two studies have shown that jellyfish collagen is an attractive alternative to mammalian collagen currently available. It has similar proliferation characteristics, induces the same morphology in cells and is not cytotoxic.
 
Other Advantages of Jellyfish Collagen: Jellyfish collagen has a significant advantage over rat tail collagen in that it can be used in clinical applications and, unlike all mammalian collagens, it is disease vector free (eg free of BSE). This makes jellyfish collagen a preferable alternative to mammalian collagen at research level, as the collagen and all associated results can be translated directly into the clinical application without complication. For researchers and scientists who want to generate more meaningful data that can be brought from the lab to clinical realisation, Jellyfish collagen provides a viable and effective collagen biomaterial.
 
Features:
  Available in both in solution and as dried collagen
  >90% pure functional collagen
  Preserved triple helix structure
  Performs as well as Rat tail (but has the added benefit of being human biocompatible) and performs better than Bovine
Applications:
  3D scaffolds for cell culture and medical research.
  Suitable for a wide variety of cell culture applications
  Biomaterial coatings
  Suitable for electrospinning
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